The pattern of proteinuria following karate (Kumite) competitions

However, despite the well-known antiproteinuric effect of Ang II antagonists [2–6], in none of these cases was a similar treatment undertaken alone. We feel that in our patient Ang II antagonists were credited with an unexpected success and avoided the toxic effects of corticosteroids and/or of immunosuppressive medications. We admit that a spontaneous remission cannot be ruled out, as it has been observed in up to one-third of adults with MCD [7,8]. However, in such a case it is slowly obtained and requires a mean time of 79 weeks [7]. This leads to believe that Ang II antagonists were the best explanation for the rapid remission in our patient. This case prompts us to suggest that Ang II antagonists should be systematically tried in MCD and that corticosteroids might be avoided with this symptomatic first line treatment, a treatment that has the advantage of being devoid of major side effects.